(E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane

Base Information

• Chemical Name: (E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane
• CAS No.: 817628-41-4
• Molecular Formula: C₁₉H₂₄Si
• Molecular Weight: 280.485
• Mol file: 817628-41-4.mol

Synonyms:(E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane

Chemical Property of (E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane

There total 1 articles about (E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-phenyl-1-pentyne (1823-14-9) → (E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane (817628-41-4)

Guidance literature:

Multi-step reaction with 2 steps

1.1: DIBAL / hexane / 20 - 50 °C

1.2: I₂ / tetrahydrofuran / 0.5 h / 0 °C

2.1: 80 percent / t-BuLi / diethyl ether; hexane / -78 - 20 °C

With tert.-butyl lithium; diisobutylaluminium hydride; In diethyl ether; hexane;

DOI:10.1021/jo048746t

Reference yield: 99.0%

(E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane (817628-41-4) + N,N-dibenzyl-O-benzoylhydroxylamine (52742-32-2) → (R)-N,N-dibenzyl-1-(dimethyl(phenyl)silyl)-5-phenylpentan-1-amine

Guidance literature:

With diethoxymethylane; (R)-DTBM-segphos; copper diacetate; In tetrahydrofuran; at 40 ℃; for 36h; enantioselective reaction; Sealed tube; Inert atmosphere;

DOI:10.1002/anie.201410326

Reference yield: 82.0%

(E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane (817628-41-4) + iodobenzene (591-50-4) → 5-phenylpent-1-ene (1075-74-7) + (E)-β-(3-phenyl-1-propyl)styrene (97455-11-3)

Guidance literature:

(E)-dimethyl(phenyl)(5-phenylpent-1-en-1-yl)silane; With 18-crown-6 ether; potassium trimethylsilonate; In tetrahydrofuran; at 20 ℃; for 0.5h;

iodobenzene; With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; In tetrahydrofuran; for 2h; Heating;

DOI:10.1021/jo048746t

upstream raw materials:

5-phenyl-1-pentyne

Downstream raw materials:

5-phenylpent-1-ene

(E)-β-(3-phenyl-1-propyl)styrene

pent-4-ene-1,4-diyldibenzene