[2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide

Base Information

• Chemical Name: [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide
• CAS No.: 864249-11-6
• Molecular Formula: C₁₆H₁₃ClN₄O₂
• Molecular Weight: 328.758

Synonyms:[2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide

Chemical Property of [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide

There total 2 articles about [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethyl [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetate (864249-10-5) → [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide (864249-11-6)

Guidance literature:

With hydrazine hydrate; In ethanol; for 6h; Heating;

Reference yield:

1,2-dihydro-3-(o-chlorophenyl)-1,8-naphthyridin-2-one (845533-61-1) → [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide (864249-11-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 96 percent / anhydrous K₂CO₃ / dimethylformamide / 0.07 h / microwave irradiation

2: 90 percent / hydrazine hydrate / ethanol / 6 h / Heating

With potassium carbonate; hydrazine hydrate; In ethanol; N,N-dimethyl-formamide;

Reference yield: 98.0%

[2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide (864249-11-6) + 4-methyl-benzaldehyde (104-87-0) → [3-(2-chloro-phenyl)-2-oxo-2H-[1,8]naphthyridin-1-yl]-acetic acid (4-methyl-benzylidene)-hydrazide (864249-02-5)

Guidance literature:

In N,N-dimethyl-formamide; for 0.025h; microwave irradiation;

upstream raw materials:

ethyl [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetate

1,2-dihydro-3-(o-chlorophenyl)-1,8-naphthyridin-2-one

Downstream raw materials:

[3-(2-Chloro-phenyl)-2-oxo-2H-[1,8]naphthyridin-1-yl]-acetic acid [1-benzo[1,3]dioxol-5-yl-meth-(E)-ylidene]-hydrazide

[3-(2-chloro-phenyl)-2-oxo-2H-[1,8]naphthyridin-1-yl]-acetic acid (4-methyl-benzylidene)-hydrazide

[3-(2-Chloro-phenyl)-2-oxo-2H-[1,8]naphthyridin-1-yl]-acetic acid [1-(4-chloro-phenyl)-meth-(E)-ylidene]-hydrazide

[3-(2-Chloro-phenyl)-2-oxo-2H-[1,8]naphthyridin-1-yl]-acetic acid [1-(2-chloro-phenyl)-meth-(E)-ylidene]-hydrazide

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 864249-11-6 [2-oxo-3-(o-chlorophenyl)-2H-[1,8]naphthyridin-1-yl] acetic acid hydrazide

Send

Send

Metric Ton KG G Pound L ML

Send

Send