4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine

Base Information

Chemical Name:4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine
CAS No.:1605945-22-9
Molecular Formula:C₁₅H₁₀F₄N₄O
Molecular Weight:338.264
Hs Code.:

Synonyms:4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine

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Chemical Property of 4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine

Chemical Property:

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Technology Process of 4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine

There total 4 articles about 4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1607442-65-8
2-(4-fluorophenyl)-2,3-dihydro-5-methyl-4H-1,2,3-triazol-4-one

: 131748-14-6
4-chloro-2-trifluoromethylpyridine

: 1605945-22-9
4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 100 ℃; for 20h; Inert atmosphere;

Reference yield:

: 823-85-8
4-fluorophenyhydrazine hydrochloride

: 1605945-22-9
4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine

Guidance literature:: Multi-step reaction with 4 steps

1.1: diethyl ether / 16 h / 23 °C

1.2: 2 h / Reflux

2.1: 28 h / Reflux

3.1: sodium hydroxide / methanol / 18 h / 23 °C

4.1: potassium carbonate / N,N-dimethyl-formamide / 20 h / 100 °C / Inert atmosphere

With potassium carbonate; sodium hydroxide; In methanol; diethyl ether; N,N-dimethyl-formamide;

Reference yield:

: 1607442-63-6
2-(4-fluorophenyl)-4-methyl-2H-1,2,3-triazole 1-oxide

: 1605945-22-9
4-[[2-(4-fluorophenyl)-5-methyl-2H-1,2,3-triazol-4-yl]oxy]-2-(trifluoromethyl)pyridine

Guidance literature:: Multi-step reaction with 3 steps

1: 28 h / Reflux

2: sodium hydroxide / methanol / 18 h / 23 °C

3: potassium carbonate / N,N-dimethyl-formamide / 20 h / 100 °C / Inert atmosphere

With potassium carbonate; sodium hydroxide; In methanol; N,N-dimethyl-formamide;