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Nitrite

Base Information
  • Chemical Name:Nitrite
  • CAS No.:14797-65-0
  • Deprecated CAS:12183-96-9,114466-53-4,1092528-35-2,114466-53-4
  • Molecular Formula:NO2
  • Molecular Weight:46.01
  • Hs Code.:
  • UN Number:2627
  • UNII:J39976L608
  • DSSTox Substance ID:DTXSID5024219
  • Nikkaji Number:J95.225G
  • Wikipedia:Nitrite ion
  • Wikidata:Q213788
  • NCI Thesaurus Code:C120467
  • RXCUI:1546424
  • Mol file:14797-65-0.mol
Nitrite

Synonyms:Nitrite;Nitrites

Suppliers and Price of Nitrite
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
Total 8 raw suppliers
Chemical Property of Nitrite
Chemical Property:
  • Boiling Point:°Cat760mmHg 
  • Flash Point:°C 
  • PSA:49.66000 
  • Density:g/cm3 
  • LogP:0.14200 
  • XLogP3:-0.8
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:3
  • Rotatable Bond Count:0
  • Exact Mass:45.992903243
  • Heavy Atom Count:3
  • Complexity:7.5
  • Transport DOT Label:Oxidizer
Purity/Quality:

98%min *data from raw suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:N(=O)[O-]
  • Recent ClinicalTrials:Three New Ideas to Protect Special Forces From the Stress of High Altitude
  • General Description Nitrite (NO2-) is a reactive nitrogen species involved in various physiological and pathological processes, including vasodilation, antimicrobial activity, and signaling pathways. It can act as a precursor for nitric oxide (NO) under hypoxic conditions, playing a role in cardiovascular and immune regulation. However, excessive nitrite levels may contribute to nitrosative stress and cellular damage due to its potential to form reactive nitrogen intermediates. Its dual role as both a beneficial signaling molecule and a toxic agent depends on concentration, redox environment, and biological context.
Refernces

Phosphinate selective hosts and importance of C–H hydrogen bonding for affinity modulation toward anion guests

10.1016/j.tetlet.2018.03.066

The research aims to develop selective anion receptors that utilize weak C-H hydrogen bonds, with a focus on phosphinate receptors. Phosphinates are significant in nature due to their association with metabolic diseases and conditions like obesity, NASH, hypercholesterolemia, and diabetes. The researchers designed and synthesized three receptors (1, 2, and 3) that utilize both amide N-H and alpha C-H (Cα-H) to the carbonyl group, differing in the substituent group attached to the alpha carbon, which affects the polarity of the CαH bond and thus the strength of association with anion guests. The study concluded that host 3, with a positively charged pyridinium group, showed the highest binding affinity due to the increased polarity of the Cα-H bond, demonstrating the importance of C-H hydrogen bonding as a modulating element for anionic recognition. Key chemicals used in the synthesis include 1,2-phenylenediamine, acetic acid, cyanoacetic acid, chloroacetyl chloride, pyridine, and various anions for testing, such as dimethyl phosphinate, benzoate, nitrite, and others.

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