(+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene

Base Information

• Chemical Name: (+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene
• CAS No.: 85185-37-1
• Molecular Formula: C₁₇H₁₈O
• Molecular Weight: 238.329
• Mol file: 85185-37-1.mol

Synonyms:(+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene

Chemical Property of (+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene

There total 9 articles about (+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(E)-1,4-diphenylbut-1-ene (27066-35-9) → (+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene (85185-37-1)

Guidance literature:

With N,N-dimethyl acetamide; In n-heptane; dichloromethane; at 20 ℃; for 1h;

DOI:10.1021/jo00157a017

Reference yield:

trans-1-Phenyl-2-hydroxymethyl-1,2-dihydro-naphthalin → (+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene (85185-37-1)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

Reference yield:

5-Phenyl-benzobicyclo<4.1.0>hepten-(3)-ol-(2) → (+/-)-trans-2-hydroxymethyl-1-phenyl-1.2.3.4-tetrahydro-naphthalene (85185-37-1)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. H₂SO₄ / diethyl ether

2: H₂ / Pd-C / ethanol

With sulfuric acid; hydrogen; palladium on activated charcoal; In diethyl ether; ethanol;

upstream raw materials:

(+/-)-trans-1-phenyl-1,2,3,4-tetrahydro-naphthoic acid-⁽²⁾

(E)-1,4-diphenylbut-1-ene

(3-phenylpropyl)triphenylphosphonium bromide

benzaldehyde