(Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate

Base Information

• Chemical Name: (Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate
• CAS No.: 1191052-81-9
• Molecular Formula: C₂₉H₂₀BrNO₄
• Molecular Weight: 526.386
• Mol file: 1191052-81-9.mol

Synonyms:(Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate

Chemical Property of (Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate

There total 1 articles about (Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

methyl 4-(2-acetoxy-5-phenyl-1H-pyrrol-1-yl)benzoate (1191052-68-2) + 5-(4-bromophenyl)-2-furancarboxyaldehyde (20005-42-9) → (Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate (1191052-81-9)

Guidance literature:

methyl 4-(2-acetoxy-5-phenyl-1H-pyrrol-1-yl)benzoate; With sodium tetrahydroborate; In methanol; at 0 ℃; for 2h; Inert atmosphere;

5-(4-bromophenyl)-2-furancarboxyaldehyde; With sodium acetate; acetic anhydride; at 100 ℃; for 0.333333h; Inert atmosphere;

DOI:10.1021/jm900707n

Reference yield: 95.0%

(Z)-methyl 4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoate (1191052-81-9) → (Z)-4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid (1191052-37-5)

Guidance literature:

With lithium iodide; In pyridine; at 23 ℃; Inert atmosphere; Reflux;

DOI:10.1021/jm900707n

upstream raw materials:

methyl 4-(2-acetoxy-5-phenyl-1H-pyrrol-1-yl)benzoate

5-(4-bromophenyl)-2-furancarboxyaldehyde

Downstream raw materials:

(Z)-4-(3-((5-(4-bromophenyl)furan-2-yl)methylene)-2-oxo-5-phenyl-2,3-dihydro-1H-pyrrol-1-yl)benzoic acid