(2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

Base Information

Chemical Name:(2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid
CAS No.:206126-53-6
Molecular Formula:C₁₆H₂₁NO₈
Molecular Weight:355.345
Hs Code.:

Synonyms:(2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

Suppliers and Price of (2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

There total 7 articles about (2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 909257-20-1
methyl-(2-benzyloxycarbonylamino-O³-methyl-2-deoxy-α-D-glucopyranoside)

: 206126-53-6
(2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

Guidance literature:: With sodium hypochlorite; tetrabutyl-ammonium chloride; potassium bromide; 2,2,6,6-tetramethyl-piperidine-N-oxyl; In water; at 0 ℃;
DOI:10.1021/jo980164m

Reference yield:

: 3006-58-4,13030-01-8,42890-10-8,42973-23-9,77059-32-6,121785-09-9,7474-40-0
2-carbobenzyloxyamino-2-deoxy-D-glucopyranose

: 206126-53-6
(2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

Guidance literature:: Multi-step reaction with 5 steps

1: HCl / dioxane / 60 °C

2: p-TsOH / dimethylformamide / 20 °C

3: NaH / tetrahydrofuran / 20 °C

4: p-TsOH; Amberlite / 20 °C

5: NaOCl; n-Bu₄NCl; KBr / 2,2,6,6-tetramethyl-1-piperidinyloxy / H₂O / 0 °C

With hydrogenchloride; sodium hypochlorite; Amberlite; tetrabutyl-ammonium chloride; sodium hydride; toluene-4-sulfonic acid; potassium bromide; 2,2,6,6-tetramethyl-piperidine-N-oxyl; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide; 1: Methylation / 2: Cyclization / 3: Methylation / 4: Ring cleavage / 5: Oxidation;
DOI:10.1021/jo980164m

Reference yield:

: 1078691-95-8
(+)-D-glucosamine hydrochloride

: 206126-53-6
(2S,3S,4R,5R,6S)-5-Benzyloxycarbonylamino-3-hydroxy-4,6-dimethoxy-tetrahydro-pyran-2-carboxylic acid

Guidance literature:: Multi-step reaction with 6 steps

1: Na₂CO₃ / H₂O / 4 °C

2: HCl / dioxane / 60 °C

3: p-TsOH / dimethylformamide / 20 °C

4: NaH / tetrahydrofuran / 20 °C

5: p-TsOH; Amberlite / 20 °C

6: NaOCl; n-Bu₄NCl; KBr / 2,2,6,6-tetramethyl-1-piperidinyloxy / H₂O / 0 °C

With hydrogenchloride; sodium hypochlorite; Amberlite; tetrabutyl-ammonium chloride; sodium hydride; sodium carbonate; toluene-4-sulfonic acid; potassium bromide; 2,2,6,6-tetramethyl-piperidine-N-oxyl; In tetrahydrofuran; 1,4-dioxane; water; N,N-dimethyl-formamide; 1: Acylation / 2: Methylation / 3: Cyclization / 4: Methylation / 5: Ring cleavage / 6: Oxidation;
DOI:10.1021/jo980164m