N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester

Base Information

Chemical Name:N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester
CAS No.:1590450-50-2
Molecular Formula:C₂₈H₂₈ClNO₅S
Molecular Weight:526.053
Hs Code.:

Synonyms:N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester

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Technology Process of N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester

There total 2 articles about N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1590450-42-2
N-benzoyl-O-[α-bromo-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester

: 108-98-5
thiophenol

: 1590450-50-2
N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester

Guidance literature:: With potassium carbonate; In toluene; at 20 ℃; for 4h; stereoselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.201301539

Reference yield:

: 157943-64-1
N-benzoyl-L-threonine isopropyl ester

: 1590450-50-2
N-benzoyl-O-[α-phenylthio-α-(p-chlorophenyl)acetyl]-L-threonine isopropyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide; dmap / dichloromethane / 20 °C / Inert atmosphere

2: potassium carbonate / toluene / 4 h / 20 °C / Inert atmosphere

With dmap; potassium carbonate; dicyclohexyl-carbodiimide; In dichloromethane; toluene;
DOI:10.1002/ejoc.201301539