Technology Process of 1-methoxy-4-((3E,7E)-4,8,10-trimethylundeca-3,7,9-trienyl)benzene
There total 7 articles about 1-methoxy-4-((3E,7E)-4,8,10-trimethylundeca-3,7,9-trienyl)benzene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium dihydrogenphosphate; sodium amalgam;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 12h;
Further stages;
Inert atmosphere;
DOI:10.1021/ja4125093
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: phosphorus tribromide / tetrahydrofuran / 0 °C / Inert atmosphere
2.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
2.2: 12 h / 23 °C / Inert atmosphere
3.1: sodium dihydrogenphosphate; sodium amalgam / tetrahydrofuran; methanol / 12 h / 20 °C / Inert atmosphere
With
sodium dihydrogenphosphate; sodium amalgam; phosphorus tribromide; lithium diisopropyl amide;
In
tetrahydrofuran; methanol;
DOI:10.1021/ja4125093
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium / tetrahydrofuran / 0.5 h / -78 - 23 °C / Inert atmosphere
1.2: 24 h / 0 °C / Inert atmosphere
2.1: potassium carbonate; methanol / 6 h / 23 °C / Inert atmosphere
3.1: phosphorus tribromide / tetrahydrofuran / 0 °C / Inert atmosphere
4.1: lithium diisopropyl amide / tetrahydrofuran / 0.5 h / -78 °C / Inert atmosphere
4.2: 12 h / 23 °C / Inert atmosphere
5.1: sodium dihydrogenphosphate; sodium amalgam / tetrahydrofuran; methanol / 12 h / 20 °C / Inert atmosphere
With
methanol; sodium dihydrogenphosphate; n-butyllithium; sodium amalgam; phosphorus tribromide; potassium carbonate; lithium diisopropyl amide;
In
tetrahydrofuran; methanol;
DOI:10.1021/ja4125093
