alpha-Cyclopentylmandelic acid, (-)-

Base Information

Chemical Name:alpha-Cyclopentylmandelic acid, (-)-
CAS No.:64471-43-8
Molecular Formula:C₁₃H₁₆O₃
Molecular Weight:220.268
Hs Code.:
UNII:E3DQW44KMU
Nikkaji Number:J2.183.870E

Synonyms:64471-43-8;E3DQW44KMU;(S)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid;alpha-Cyclopentylmandelic acid, (-)-;(2S)-2-cyclopentyl-2-hydroxy-2-phenylacetic acid;(2~{S})-2-cyclopentyl-2-oxidanyl-2-phenyl-ethanoic acid;UNII-E3DQW44KMU;SCHEMBL2062949;(-)-alpha-cyclopentylmandelic acid;CS-0120802;.ALPHA.-CYCLOPENTYLMANDELIC ACID, (-)-;Q27276819;BENZENEACETIC ACID, .ALPHA.-CYCLOPENTYL-.ALPHA.-HYDROXY-, (S)-;BENZENEACETIC ACID, .ALPHA.-CYCLOPENTYL-.ALPHA.-HYDROXY-, (.ALPHA.S)-;VCQ

Suppliers and Price of alpha-Cyclopentylmandelic acid, (-)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of alpha-Cyclopentylmandelic acid, (-)-

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:220.109944368
Heavy Atom Count:16
Complexity:252

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCC(C1)C(C2=CC=CC=C2)(C(=O)O)O
Isomeric SMILES:C1CCC(C1)[C@](C2=CC=CC=C2)(C(=O)O)O

Technology Process of alpha-Cyclopentylmandelic acid, (-)-

There total 18 articles about alpha-Cyclopentylmandelic acid, (-)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 302842-81-5
(S)-α-(cyclopentyl-1-ene)-α-hydroxy-α-phenylacetic acic

: 64471-43-8
(S)-α-cyclopentyl-α-hydroxy-α-phenylacetic acid

Guidance literature:: With hydrogen; 10percent Pd/C; In methanol; for 18h; under 760.051 Torr;
DOI:10.1021/jo005562f

Reference yield: 62.0%

: 937179-77-6
cis-(2S,5S)-2-(tert-butyl)-5-phenyl-5-cyclopentyl-1,3-dioxolan-4-one

: 64471-43-8
(S)-α-cyclopentyl-α-hydroxy-α-phenylacetic acid

Guidance literature:: cis-(2S,5S)-2-(tert-butyl)-5-phenyl-5-cyclopentyl-1,3-dioxolan-4-one; With potassium hydroxide; water; In methanol; at 65 ℃; for 3 - 4h; Heating / reflux;

With hydrogenchloride; In water; ethyl acetate; pH=1;

Reference yield: 33.3%

: 427-49-6
2-cyclopentyl-2-hydroxy-2-phenylacetic acid

: 64471-43-8
(S)-α-cyclopentyl-α-hydroxy-α-phenylacetic acid

Guidance literature:: 2-cyclopentyl-2-hydroxy-2-phenylacetic acid; With strychnidin-10-one; In methanol; at 20 ℃; Resolution of racemate;

With sodium hydroxide; In water;

With hydrogenchloride; In water;
DOI:10.1691/ph.2008.7775