7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde

Base Information

• Chemical Name: 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde
• CAS No.: 155371-24-7
• Molecular Formula: C₁₅H₁₇NO₂
• Molecular Weight: 243.305
• Mol file: 155371-24-7.mol

Synonyms:7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde

Chemical Property of 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde

There total 2 articles about 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

3a-methyl-2-phenyl-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine-3-carbaldehyde (155371-20-3) → 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde (155371-24-7) + 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde

Guidance literature:

In benzene; at 20 ℃; for 0.6h; Irradiation;

DOI:10.1039/c39940000301

Reference yield:

Phenylpropargyl aldehyde (2579-22-8) → 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde (155371-24-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 80 percent / ethanol / Heating

2: 88 percent / benzene / 0.6 h / Irradiation

In ethanol; benzene;

DOI:10.1002/ejoc.200390203

Reference yield: 78.0%

4-methyl-1,2,4-triazoline-3,5-dione (13274-43-6) + 7-benzoyl-6-methyl-1-azabicyclo[4.1.0]heptane-7-carbaldehyde (155371-24-7) → 6-benzoyl-5-hydroxy-2,11a-dimethyl-9,10,11,11a-tetrahydro-1H,8H-pyrido[2,1-c][1,2,4]triazolo[1,2-a][1,2,4]triazine-1,3(2H)-dione

Guidance literature:

In dichloromethane; at 20 ℃; for 0.333333h;

DOI:10.1002/ejoc.200390203

upstream raw materials:

3a-methyl-2-phenyl-4,5,6,7-tetrahydro-3aH-isoxazolo[2,3-a]pyridine-3-carbaldehyde

Phenylpropargyl aldehyde