Chlordiazepoxide

Base Information Edit

Chemical Name:Chlordiazepoxide
CAS No.:58-25-3
Molecular Formula:C16H14ClN3O
Molecular Weight:299.76
Hs Code.:2933910000
European Community (EC) Number:200-371-0
UNII:6RZ6XEZ3CR
DSSTox Substance ID:DTXSID40861935
Nikkaji Number:J2.332I
Wikipedia:Chlordiazepoxide
Wikidata:Q178566
NCI Thesaurus Code:C47443
RXCUI:2356
Pharos Ligand ID:531SMB643Q29
ChEMBL ID:CHEMBL451
Mol file:58-25-3.mol

Synonyms:7 Chloro 2 methylamino 5 phenyl 3H 1,4 benzodiazepine 4 oxide;7 Chloro N methyl 5 phenyl 3H 1,4 benzodiazepin 2 amine 4 oxide;7-chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine-4-oxide;7-Chloro-N-methyl-5-phenyl-3H-1,4-benzodiazepin-2-amine 4-oxide;Chlordiazepoxide;Chlordiazepoxide Hydrobromide;Chlordiazepoxide Hydrochloride;Chlordiazepoxide Monohydrochloride;Chlordiazepoxide Perchlorate;Chlozepid;Elenium;Hydrobromide, Chlordiazepoxide;Hydrochloride, Chlordiazepoxide;Librium;Methaminodiazepoxide;Monohydrochloride, Chlordiazepoxide;Perchlorate, Chlordiazepoxide

This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Chlordiazepoxide Edit

Chemical Property:

Appearance/Colour:Light yellow crystalline powder
Vapor Pressure:4.18E-12mmHg at 25°C
Melting Point:236- 236.5 °C
Refractive Index:1.6490 (estimate)
Boiling Point:549.041 °C at 760 mmHg
PKA:4.8(at 25℃)
Flash Point:285.85 °C
PSA：53.14000
Density:1.3 g/cm³
LogP:2.73600
Storage Temp.:Controlled Substance, -20?C Freezer, Under Inert Atmosphere
Solubility.:Practically insoluble in water, sparingly soluble in ethanol (96 per cent)
Water Solubility.:2g/L(room temperature)
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:299.0825398
Heavy Atom Count:21
Complexity:580

Purity/Quality:

Safty Information:

Pictogram(s): F,T
Hazard Codes:F,T
Statements: 11-23/24/25-39/23/24/25
Safety Statements: 7-16-36/37-45

MSDS Files:: SDS file from LookChem

Useful:

Drug Classes:Benzodiazepines
Canonical SMILES:CN=C1CN(C(=C2C=C(C=CC2=N1)Cl)C3=CC=CC=C3)O
Recent ClinicalTrials:Agaricus Bisporus and Influenza Vaccination Response
Recent EU Clinical Trials:Association between variations in CYP pheno- and genotypes and plasma concentration of chlordiazepoxide in the treatment of alcohol withdrawal symptoms
Uses Controlled substance (depressant). Anxiolytic. Prototype of the benzodiazepine anxiolytics
Therapeutic Function Tranquilizer

Technology Process of Chlordiazepoxide

There total 2 articles about Chlordiazepoxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: