4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide

Base Information

• Chemical Name: 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide
• CAS No.: 1382052-37-0
• Molecular Formula: C₂₀H₁₇N₅O₂S₂
• Molecular Weight: 423.519

Synonyms:4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide

Chemical Property of 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide

There total 4 articles about 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

2-cyano-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)acetamide (1382052-05-2) + phenyl isothiocyanate (103-72-0) → 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide (1382052-37-0)

Guidance literature:

With sulfur; triethylamine; In ethanol; for 3h; Reflux;

DOI:10.1016/j.ejmech.2012.03.044

Reference yield:

2-Amino-5-methylbenzoic acid (2941-78-8) → 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide (1382052-37-0)

Guidance literature:

Multi-step reaction with 4 steps

1: Reflux

2: hydrazine hydrate / Reflux

3: Reflux

4: sulfur; triethylamine / ethanol / 3 h / Reflux

With sulfur; hydrazine hydrate; triethylamine; In ethanol;

DOI:10.1016/j.ejmech.2012.03.044

Reference yield:

2-methyl-6-methyl-4H-3,1-benzoxazin-4-one (62175-49-9) → 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide (1382052-37-0)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / Reflux

2: Reflux

3: sulfur; triethylamine / ethanol / 3 h / Reflux

With sulfur; hydrazine hydrate; triethylamine; In ethanol;

DOI:10.1016/j.ejmech.2012.03.044

upstream raw materials:

2-Amino-5-methylbenzoic acid

2-methyl-6-methyl-4H-3,1-benzoxazin-4-one

2-cyano-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)acetamide

phenyl isothiocyanate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1382052-37-0 4-amino-2,3-dihydro-N-(2,6-dimethyl-4-oxoquinazolin-3(4H)-yl)-3-phenyl-2-thioxothiazole-5-carboxamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send