ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate

Base Information

Chemical Name:ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate
CAS No.:210161-80-1
Molecular Formula:C₁₇H₂₅ClN₂O₆
Molecular Weight:388.848
Hs Code.:

Synonyms:ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate

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Technology Process of ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate

There total 2 articles about ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1943-83-5
2-chloroethyl isothiocyanate

: 2-ethoxycarbonyl(3,4,5-trimethoxyphenyl)ethylammonium chloride

: 210161-80-1
ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate

Guidance literature:: With triethylamine; In chloroform; at 20 ℃; for 2h;

Reference yield:

: 34841-00-4,171002-25-8
β-amino-β-(3,4,5-trimethoxyphenyl)propionic acid

: 210161-80-1
ethyl-3-[3N'-(2-chloroethyl)ureido]-3-(3,4,5-trimethoxyphenyl)propionate

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / thionyl chloride / ethanol / 5 h / Heating

2: 95 percent / triethylamine / CHCl₃ / 2 h / 20 °C

With thionyl chloride; triethylamine; In ethanol; chloroform; 1: Esterification / 2: Addition;