Leurubicin

Base Information

Chemical Name:Leurubicin
CAS No.:70774-25-3
Molecular Formula:C33H40N2O12
Molecular Weight:656.681
Hs Code.:
Mol file:70774-25-3.mol

Synonyms:L-Leucyldoxorubicin;N-leucyldoxorubicin;leucine-doxorubicin;N-(L-Leucyl)doxorubicin;

Suppliers and Price of Leurubicin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
LEURUBICIN 95.00%
5MG
$ 503.55

Total 5 raw suppliers

Chemical Property of Leurubicin

Chemical Property:

Vapor Pressure:0mmHg at 25°C
Boiling Point:916.2°C at 760 mmHg
Flash Point:507.9°C
PSA：235.17000
Density:1.49g/cm³
LogP:1.62340

Purity/Quality:

≥90% ^*data from raw suppliers

LEURUBICIN 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Leurubicin is a prodrug of the antracycline Doxorubicin Hydrochloride(D558000) which is an antineoplastic agent.

Technology Process of Leurubicin

There total 1 articles about Leurubicin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: MJ₀₂

: Cbz-Gly-Pro-Ile-Gln-Glu-Homophe

: 70774-25-3
N-(L-leucyl)doxorubicin

Guidance literature:: With recombinant human MMP-2; In aq. buffer; at 37 ℃; for 12h; pH=7.6; Enzymatic reaction;
DOI:10.1021/acs.jmedchem.6b01472

Reference yield: 93.0%

: C₁₇H₂₂NO₅Pol

: 70774-25-3
N-(L-leucyl)doxorubicin

: C₅₀H₆₀N₃O₁₆Pol

Guidance literature:: With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In DMF (N,N-dimethyl-formamide); at 0 - 20 ℃;

Reference yield: 90.0%

: C₁₇H₂₂NO₅Pol

: 70774-25-3
N-(L-leucyl)doxorubicin

: C₅₀H₆₀N₃O₁₆Pol

Guidance literature:: With 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; In dichloromethane; at 20 ℃;