Technology Process of (Z)-1,1,1-trifluoro-3-phenylprop-2-en-2-yl diphenylphosphinate
There total 1 articles about (Z)-1,1,1-trifluoro-3-phenylprop-2-en-2-yl diphenylphosphinate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
1,1,1-Trifluoro-3-phenylpropan-2-one;
With
lithium hexamethyldisilazane;
In
tetrahydrofuran;
at -78 ℃;
for 0.5h;
Inert atmosphere;
Diphenylphosphinic chloride;
In
tetrahydrofuran;
at -78 - 20 ℃;
Inert atmosphere;
DOI:10.1002/adsc.200800645
- Guidance literature:
-
With
C32H12BF24(1-)*C38H38IrNPS(1+); hydrogen;
In
dichloromethane;
at 20 ℃;
for 24h;
under 37503.8 Torr;
optical yield given as %ee;
enantioselective reaction;
DOI:10.1002/adsc.200800645
