C₃₀H₄₃N₅O₄S

Base Information

• Chemical Name: C₃₀H₄₃N₅O₄S
• CAS No.: 1357007-77-2
• Molecular Formula: C₃₀H₄₃N₅O₄S
• Molecular Weight: 569.769
• Mol file: 1357007-77-2.mol

Synonyms:C₃₀H₄₃N₅O₄S

Chemical Property of C₃₀H₄₃N₅O₄S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₄₃N₅O₄S

There total 9 articles about C₃₀H₄₃N₅O₄S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

C31H45N5O6S → C30H43N5O4S (1357007-77-2)

Guidance literature:

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; HATU; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one; In dichloromethane; acetonitrile; for 12h;

DOI:10.1016/j.tet.2011.11.089

Reference yield:

C6H14N2S (114747-11-4) → C30H43N5O4S (1357007-77-2)

Guidance literature:

Multi-step reaction with 6 steps

1.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; HATU / dichloromethane / 1.5 h / 20 °C / Inert atmosphere

2.1: potassium hydrogencarbonate / 1,2-dimethoxyethane / 0.25 h / 20 °C / Inert atmosphere

3.1: pyridine; triethylamine; trifluoroacetic anhydride / 1,2-dimethoxyethane / 0 °C / Inert atmosphere

4.1: dihydrogen peroxide; lithium hydroxide / methanol / 3 h / 20 °C

4.2: pH 1

5.1: methoxybenzene; trifluoroacetic acid / dichloromethane / 0.67 h

6.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; HATU; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one / dichloromethane; acetonitrile / 12 h

With pyridine; dihydrogen peroxide; potassium hydrogencarbonate; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; methoxybenzene; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; trifluoroacetic anhydride; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one; lithium hydroxide; In methanol; 1,2-dimethoxyethane; dichloromethane; acetonitrile;

DOI:10.1016/j.tet.2011.11.089

Reference yield:

C36H57N5O7S → C30H43N5O4S (1357007-77-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: pyridine; triethylamine; trifluoroacetic anhydride / 1,2-dimethoxyethane / 0 °C / Inert atmosphere

2.1: dihydrogen peroxide; lithium hydroxide / methanol / 3 h / 20 °C

2.2: pH 1

3.1: methoxybenzene; trifluoroacetic acid / dichloromethane / 0.67 h

4.1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; HATU; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one / dichloromethane; acetonitrile / 12 h

With pyridine; dihydrogen peroxide; O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; methoxybenzene; triethylamine; N-ethyl-N,N-diisopropylamine; HATU; trifluoroacetic acid; trifluoroacetic anhydride; 3-[(diethoxyphosphinyl)oxy]-1,2,3-benzotriazin-4(3H)-one; lithium hydroxide; In methanol; 1,2-dimethoxyethane; dichloromethane; acetonitrile;

DOI:10.1016/j.tet.2011.11.089

upstream raw materials:

C₆H₁₄N₂S

C₁₇H₃₃N₃O₃S

C₃₆H₅₅N₅O₇S

N-tert-butoxycarbonyl-(L)-leucinamide