N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine

Base Information

• Chemical Name: N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine
• CAS No.: 1258859-53-8
• Molecular Formula: C₁₉H₂₂ClF₆N₃O₃
• Molecular Weight: 489.845
• Mol file: 1258859-53-8.mol

Synonyms:N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine

Chemical Property of N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine

There total 1 articles about N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

chloro-D-amphetamine hydrochloride (1196664-72-8) + Nα,Nε-bis(trifluoroacetyl)-L-lysine (329-53-3) → N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine (1258859-53-8)

Guidance literature:

N^α,N^ε-bis(trifluoroacetyl)-L-lysine; With Vilsmeier reagent; In Isopropyl acetate; at -10 ℃;

chloro-D-amphetamine hydrochloride; With potassium carbonate; In Isopropyl acetate; at 5 - 20 ℃;

Reference yield: 85.0%

N,N'-bistrifluoroacetyl-chloro-lisdexamfetamine (1258859-53-8) → N,N'-bistrifluoroacetyl-lisdexamfetamine (1258859-54-9)

Guidance literature:

With hydrogen; sodium acetate; palladium 10% on activated carbon; In acetic acid; at 50 ℃; for 5h; Inert atmosphere;

upstream raw materials:

chloro-D-amphetamine hydrochloride

N^α,N^ε-bis(trifluoroacetyl)-L-lysine

Downstream raw materials:

N,N'-bistrifluoroacetyl-lisdexamfetamine