2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid

Base Information

Chemical Name:2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid
CAS No.:326915-38-2
Molecular Formula:C₁₄H₉ClN₂O₂S
Molecular Weight:304.757
Hs Code.:
DSSTox Substance ID:DTXSID801190935

Synonyms:326915-38-2;2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid;DTXSID801190935;STL286630;AKOS005209468;CS-0358402;{[6-(4-chlorophenyl)-3-cyanopyridin-2-yl]sulfanyl}acetic acid;2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)aceticacid;2-[[6-(4-Chlorophenyl)-3-cyano-2-pyridinyl]thio]acetic acid

Suppliers and Price of 2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:304.0073264
Heavy Atom Count:20
Complexity:390

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1C2=NC(=C(C=C2)C#N)SCC(=O)O)Cl

Technology Process of 2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid

There total 1 articles about 2-((6-(4-Chlorophenyl)-3-cyanopyridin-2-yl)thio)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 115809-11-5
6-(4-chlorophenyl)-2-thioxo-1,2-dihydropyridine-3-carbonitrile

: 79-11-8
chloroacetic acid

: 326915-38-2
{[6-(4-chlorophenyl)-3-cyanopyridin-2-yl]sulfanyl}acetic acid

Guidance literature:: With sodium methylate; In methanol; at 20 ℃; for 0.25h;
DOI:10.1080/17415993.2012.661734

Reference yield: 69.0%

: 326915-38-2
{[6-(4-chlorophenyl)-3-cyanopyridin-2-yl]sulfanyl}acetic acid

: 3-amino-6-(4-chlorophenyl)thieno[2,3-b]pyridine-2-carboxylic acid

Guidance literature:: With sodium ethanolate; In ethanol; for 3h; Reflux;
DOI:10.1080/17415993.2012.661734

Reference yield:

: 326915-38-2
{[6-(4-chlorophenyl)-3-cyanopyridin-2-yl]sulfanyl}acetic acid

: 1374993-97-1
7-(4-chlorophenyl)-2-methyl-3-(4-methylphenyl)pyrido[3',2':4,5]thieno[3,2-d]-pyrimidin-4(3H)-one

Guidance literature:: Multi-step reaction with 3 steps

1: sodium ethanolate / ethanol / 3 h / Reflux

2: 4 h / Reflux

3: acetic acid / 3 h / Reflux

With sodium ethanolate; acetic acid; In ethanol;
DOI:10.1080/17415993.2012.661734