1-Methyl-1H-indazol-4-ylamine

Base Information

• Chemical Name: 1-Methyl-1H-indazol-4-ylamine
• CAS No.: 77894-69-0
• Molecular Formula: C8H9N3
• Molecular Weight: 147.18
• Hs Code.: 2933990090
• Mol file: 77894-69-0.mol

Synonyms:1H-Indazole,4-amino-1-methyl- (7CI);1-Methyl-1H-indazol-4-amine;1-Methyl-1H-indazol-4-ylamine;4-Amino-1-methylindazole;

Chemical Property of 1-Methyl-1H-indazol-4-ylamine

Chemical Property:

• Vapor Pressure: 0.000295mmHg at 25°C
• Refractive Index: 1.667
• Boiling Point: 321.6 °C at 760 mmHg
• Flash Point: 148.3 °C
• PSA: 43.84000
• Density: 1.27 g/cm³
• LogP: 1.73670
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

97% ^*data from raw suppliers

1-methyl-1H-indazol-4-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-Methyl-1H-indazol-4-ylamine

There total 8 articles about 1-Methyl-1H-indazol-4-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-methyl-4-nitro-1H-indazole (26120-43-4) → 1-methyl-1H-indazol-4-ylamine (77894-69-0)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In ethanol; for 2h;

Reference yield: 59.0%

1-methyl-4-nitro-1H-indazole (26120-43-4) → 4-amino-7-chloro-1-methyl-1H-indazole + 1-methyl-1H-indazol-4-ylamine (77894-69-0)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; In methanol; for 1h; Heating;

Reference yield:

4-bromo-1-methyl-1H-indazole (365427-30-1) → 1-methyl-1H-indazol-4-ylamine (77894-69-0)

Guidance literature:

4-bromo-1-methyl-1H-indazole; With Benzophenone imine; palladium diacetate; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In toluene; at 20 ℃; for 0.25h; Inert atmosphere;

With sodium t-butanolate; In toluene; at 80 - 85 ℃; for 2h; Inert atmosphere;

upstream raw materials:

1-methyl-4-nitro-1H-indazole

3-nitro-o-tolylamine

nitro-4 indazole

pyrographite

Downstream raw materials:

2-[(1-methyl-1H-indazol-4-yl)amino]-3-nitrobenzoic acid

2-methyl-4-amino-2H-indazole

N-(4-tert-butylbenzyl)-N'-(1-methyl-1H-indazol-4-yl)urea

N-(2,4-dichlorobenzyl)-N'-(1-methyl-1H-indazol-4-yl)urea