Technology Process of methyl 2-nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate
There total 1 articles about methyl 2-nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
2-Isopropoxy-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; methyl 3-bromo-2-nitrobenzoate;
In
tetrahydrofuran; toluene;
at -97 ℃;
Inert atmosphere;
With
n-butyllithium;
In
tetrahydrofuran; toluene;
at -97 - -20 ℃;
Inert atmosphere;
With
acetic acid;
In
tetrahydrofuran; toluene;
at -20 - 25 ℃;
Inert atmosphere;
DOI:10.1021/jo101826p
- Guidance literature:
-
C14H9IO3; acetic anhydride;
With
pyridine; dmap;
In
dichloromethane;
for 2h;
Inert atmosphere;
methyl 2-nitro-3-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzoate;
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate tribasic; palladium diacetate;
In
tetrahydrofuran; water;
at 80 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/jo101826p
- Guidance literature:
-
With
dicyclohexyl-(2',6'-dimethoxybiphenyl-2-yl)-phosphane; potassium phosphate tribasic; palladium diacetate;
In
tetrahydrofuran; water;
at 80 ℃;
for 2h;
Inert atmosphere;
DOI:10.1021/jo101826p
