C₃₀H₂₄BrClN₄O₅

Base Information

• Chemical Name: C₃₀H₂₄BrClN₄O₅
• CAS No.: 1370472-58-4
• Molecular Formula: C₃₀H₂₄BrClN₄O₅
• Molecular Weight: 635.901
• Mol file: 1370472-58-4.mol

Synonyms:C₃₀H₂₄BrClN₄O₅

Chemical Property of C₃₀H₂₄BrClN₄O₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₂₄BrClN₄O₅

There total 4 articles about C₃₀H₂₄BrClN₄O₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-azido-N-[3-(4-bromophenyl)-1-(2-chlorophenyl)-3-oxopropyl]propanamide (1370471-07-0) + 7-(propynyloxy)-2H-chromen-2-one (67268-42-2) → C30H24BrClN4O5 (1370472-58-4)

Guidance literature:

With copper(II) sulfate pentahydrate; sodium L-ascorbate; In water; dimethyl sulfoxide; tert-butyl alcohol; at 20 ℃; for 12h; diastereoselective reaction;

DOI:10.1016/j.bmcl.2012.01.111

Reference yield:

2-chloro-benzaldehyde (89-98-5) → C30H24BrClN4O5 (1370472-58-4)

Guidance literature:

Multi-step reaction with 3 steps

1: boron trifluoride diethyl etherate; acetyl chloride / 48 h / 20 °C / Neat (no solvent)

2: sodium azide; potassium carbonate / ISOPROPYLAMIDE / 4 h / 20 °C

3: copper(II) sulfate pentahydrate; sodium L-ascorbate / water; dimethyl sulfoxide; tert-butyl alcohol / 12 h / 20 °C

With sodium azide; copper(II) sulfate pentahydrate; boron trifluoride diethyl etherate; potassium carbonate; sodium L-ascorbate; acetyl chloride; In ISOPROPYLAMIDE; water; dimethyl sulfoxide; tert-butyl alcohol; 1: Mannich reaction;

DOI:10.1016/j.bmcl.2012.01.111

Reference yield:

C18H16Br2ClNO2 → C30H24BrClN4O5 (1370472-58-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium azide; potassium carbonate / ISOPROPYLAMIDE / 4 h / 20 °C

2: copper(II) sulfate pentahydrate; sodium L-ascorbate / water; dimethyl sulfoxide; tert-butyl alcohol / 12 h / 20 °C

With sodium azide; copper(II) sulfate pentahydrate; potassium carbonate; sodium L-ascorbate; In ISOPROPYLAMIDE; water; dimethyl sulfoxide; tert-butyl alcohol;

DOI:10.1016/j.bmcl.2012.01.111

upstream raw materials:

3-azido-N-[3-(4-bromophenyl)-1-(2-chlorophenyl)-3-oxopropyl]propanamide

7-(propynyloxy)-2H-chromen-2-one

2-chloro-benzaldehyde

para-bromoacetophenone