4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide

Base Information

Chemical Name:4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide
CAS No.:847861-68-1
Molecular Formula:C₂₃H₁₈F₄N₂O₃
Molecular Weight:446.401
Hs Code.:

Synonyms:4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide

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Chemical Property of 4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide

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Technology Process of 4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide

There total 1 articles about 4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 847861-67-0
4'-trifluoromethylbiphenyl-2-carboxylic acid (4-benzyloxy-2-dimethylcarbamoyl-5-fluorophenyl)amide

: 847861-68-1
4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide

Guidance literature:: With hydrogen; palladium-carbon; In tetrahydrofuran; methanol; at 20 ℃; for 3h;

Reference yield:

: 847861-68-1
4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide

: 32315-10-9
bis(trichloromethyl) carbonate

: 278791-10-9
hydroxymethyl-phenyl-malonic acid diethyl ester

: 847860-81-5
2-{5-dimethylcarbamoyl-2-fluoro-4-[(4'-trifluoromethylbiphenyl-2-carbonyl)amino]phenoxycarbonyloxymethyl}-2-phenylmalonic acid diethyl ester

Guidance literature:: bis(trichloromethyl) carbonate; hydroxymethyl-phenyl-malonic acid diethyl ester; With N,N-dimethyl-aniline; In chloroform; at 0 - 20 ℃; for 3h;

4'-trifluoromethylbiphenyl-2-carboxylic acid (2-dimethylcarbamoyl-5-fluoro-4-hydroxyphenyl)amide; With triethylamine; In tetrahydrofuran; chloroform; at 0 - 20 ℃; for 2h;