cyclobutane-1,2-dicarboxylic acid monopropargyl ester

Base Information

• Chemical Name: cyclobutane-1,2-dicarboxylic acid monopropargyl ester
• CAS No.: 1236042-93-5
• Molecular Formula: C₉H₁₀O₄
• Molecular Weight: 182.176
• Mol file: 1236042-93-5.mol

Synonyms:cyclobutane-1,2-dicarboxylic acid monopropargyl ester

Chemical Property of cyclobutane-1,2-dicarboxylic acid monopropargyl ester

Chemical Property:

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Technology Process of cyclobutane-1,2-dicarboxylic acid monopropargyl ester

There total 1 articles about cyclobutane-1,2-dicarboxylic acid monopropargyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

cis-1,2-cyclobutane dicarboxylic anhydride (4462-96-8) + propargyl alcohol (107-19-7) → cyclobutane-1,2-dicarboxylic acid monopropargyl ester (1236042-93-5)

Guidance literature:

With C₄₁H₂₁F₁₂N₂O₂PS; In toluene; at -30 ℃; for 96h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;

DOI:10.1002/anie.201000637

upstream raw materials:

cis-1,2-cyclobutane dicarboxylic anhydride

propargyl alcohol