2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol

Base Information

• Chemical Name: 2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol
• CAS No.: 904686-44-8
• Molecular Formula: C₂₇H₂₆ClN₃O₅
• Molecular Weight: 507.974
• Mol file: 904686-44-8.mol

Synonyms:2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol

Chemical Property of 2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol

There total 1 articles about 2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

1-(2-chlorophenyl)-4-(4-propoxyphenyl)butane-1,4-dione (904686-43-7) + acetic acid 2-(6-aminomethyl-2-nitropyridin-3-yloxy)-ethyl ester (904686-42-6) → 2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol (904686-44-8)

Guidance literature:

toluene-4-sulfonic acid; In ethanol; toluene; at 100 ℃; for 72h;

Reference yield: 39.0%

2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol (904686-44-8) → 2-[(2-amino-6-{[2-(2-chlorophenyl)-5-(4-propoxyphenyl)-1H-pyrrol-1-yl]methyl}pyridine-3-yl)oxy]ethanol

Guidance literature:

2-{6-[2-(2-Chlorophenyl)-5-(4-propoxyphenyl)-pyrrol-1ylmethyl]-2-nitro-pyridin-3-yloxy}-ethanol; With iron; acetic acid; In ethanol; at 96 ℃; for 2h;

With sodium hydrogencarbonate; In ethanol; water;

upstream raw materials:

1-(2-chlorophenyl)-4-(4-propoxyphenyl)butane-1,4-dione

acetic acid 2-(6-aminomethyl-2-nitropyridin-3-yloxy)-ethyl ester