3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

Base Information

Chemical Name:3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol
CAS No.:1015081-76-1
Molecular Formula:C₂₇H₃₄FNO₂
Molecular Weight:423.571
Hs Code.:

Synonyms:3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

Suppliers and Price of 3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

There total 3 articles about 3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 1015081-72-7
3-methoxy-16β-((4'-fluorobenzylideneimino)methyl)estra-1,3,5(10)-trien-17β-ol

: 1015081-76-1
3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

Guidance literature:: With methanol; sodium tetrahydroborate; In tetrahydrofuran; at 20 ℃; for 2h;
DOI:10.1016/j.steroids.2007.02.001

Reference yield:

: 459-57-4
4-fluorobenzaldehyde

: 1015081-76-1
3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / ethanol / 2 h / Heating

2: 75 percent / NaBH₄; MeOH / tetrahydrofuran / 2 h / 20 °C

With methanol; sodium tetrahydroborate; In tetrahydrofuran; ethanol;
DOI:10.1016/j.steroids.2007.02.001

Reference yield:

: 218281-26-6
17β-hydroxy-16β-aminomethylestrone 3-methyl ether

: 1015081-76-1
3-methoxy-16β-((4'-fluorobenzylamino)methyl)estra-1,3,5(10)-trien-17β-ol

Guidance literature:: Multi-step reaction with 2 steps

1: 70 percent / ethanol / 2 h / Heating

2: 75 percent / NaBH₄; MeOH / tetrahydrofuran / 2 h / 20 °C

With methanol; sodium tetrahydroborate; In tetrahydrofuran; ethanol;
DOI:10.1016/j.steroids.2007.02.001