C₁₉H₂₄ClNO₅

Base Information

• Chemical Name: C₁₉H₂₄ClNO₅
• CAS No.: 1293966-41-2
• Molecular Formula: C₁₉H₂₄ClNO₅
• Molecular Weight: 381.856
• Mol file: 1293966-41-2.mol

Synonyms:C₁₉H₂₄ClNO₅

Chemical Property of C₁₉H₂₄ClNO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₉H₂₄ClNO₅

There total 13 articles about C₁₉H₂₄ClNO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

C9H15ClO4 (1293966-40-1) + (R)-4-(phenylmethyl)-2-oxazolidinone (40217-17-2,90719-32-7,120574-96-1,102029-44-7) → C19H24ClNO5 (1293966-41-2)

Guidance literature:

C₉H₁₅ClO₄; With pivaloyl chloride; triethylamine; In tetrahydrofuran; at -20 ℃; for 1h;

(R)-4-(phenylmethyl)-2-oxazolidinone; With lithium chloride; In tetrahydrofuran; at 0 ℃; for 3h;

DOI:10.1021/acs.orglett.9b00722

Reference yield:

C14H23ClO5 + (R)-4-(phenylmethyl)-2-oxazolidinone (40217-17-2,90719-32-7,120574-96-1,102029-44-7) → C19H24ClNO5 (1293966-41-2)

Guidance literature:

With lithium chloride; In tetrahydrofuran; at -20 - 0 ℃; Inert atmosphere;

DOI:10.1021/ol2007296

Reference yield:

C10H18O3 (1268269-17-5) → C19H24ClNO5 (1293966-41-2)

Guidance literature:

Multi-step reaction with 4 steps

1.1: 1H-imidazole; tetrachloromethane; triphenylphosphine / dichloromethane / 15.33 h / 0 - 20 °C / Inert atmosphere

2.1: sodium periodate; sodium hydrogencarbonate / tetrachloromethane; water; acetonitrile / 0.17 h / 20 °C / Inert atmosphere

2.2: 2 h / 20 °C / Inert atmosphere

3.1: triethylamine / tetrahydrofuran / 1 h / -20 °C / Inert atmosphere

4.1: lithium chloride / tetrahydrofuran / -20 - 0 °C / Inert atmosphere

With 1H-imidazole; tetrachloromethane; sodium periodate; sodium hydrogencarbonate; triethylamine; triphenylphosphine; lithium chloride; In tetrahydrofuran; tetrachloromethane; dichloromethane; water; acetonitrile;

DOI:10.1021/ol2007296

upstream raw materials:

C₁₀H₁₈O₃

C₁₀H₁₇ClO₂

C₉H₁₅ClO₄

(R)-4-(phenylmethyl)-2-oxazolidinone

Downstream raw materials:

C₅₉H₉₇ClO₁₃Si

C₆₅H₁₁₁ClO₁₃Si₂

C₂₀H₂₆ClNO₅