Chemical Property of Cyclobenzaprine Hydrochloride
Chemical Property:
- Appearance/Colour:Crystalline Solid
- Vapor Pressure:8.45E-07mmHg at 25°C
- Melting Point:216-218°C
- Boiling Point:405.9 °C at 760 mmHg
- Flash Point:177.8 °C
- PSA：3.24000
- LogP:5.35580
- Storage Temp.:-20°C Freezer
- Solubility.:≥15.59 mg/mL in DMSO; ≥5.32 mg/mL in EtOH; ≥54.3 mg/mL in H2O
- Water Solubility.:Completely soluble in water
- Hydrogen Bond Donor Count:1
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:3
- Exact Mass:311.1440774
- Heavy Atom Count:22
- Complexity:365
- Purity/Quality:
-
99% *data from raw suppliers
Cyclobenzaprine Hydrochloride *data from reagent suppliers
Safty Information:
- Pictogram(s):
- Hazard Codes:Xn,T,F
- Statements:
20/21/22-39/23/24/25-23/24/25-11
- Safety Statements:
36-45-36/37-16-7
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CN(C)CCC=C1C2=CC=CC=C2C=CC3=CC=CC=C31.Cl
- Recent ClinicalTrials:Fixed-dose Combination of Etoricoxib + Cyclobenzaprine for Pain Relief After Third Molar Extraction in Brazil
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Description
Cyclobenzaprine is a skeletal muscle relaxant that also has sedative properties. It has been shown to antagonize muscarinic receptors (Kis = 25, 60, and 6 nM for M1, M2, and M3, respectively), serotonin 5-HT2 receptors (Kis = 56 and 330 nM for 5-HT2C and 5-HT2B, respectively), and histamine H1 receptor (IC50 = 20 nM).
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Uses
Cyclobenzaprine hydrochloride cam be used as muscle relaxant (skeletal). Cyclobenzaprine hydrochloride can be used as a serotonin receptor inhibitor. Cyclobenzaprine hydrochloride has been used to study its effect on the muscles of dystrophin-deficient mdx5Cv mice.
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Therapeutic Function
Muscle relaxant
