(3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

Base Information

Chemical Name:(3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea
CAS No.:1169705-55-8
Molecular Formula:C₂₁H₂₅ClN₄OS₂
Molecular Weight:449.041
Hs Code.:

Synonyms:(3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

Chemical Property:

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Technology Process of (3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

There total 10 articles about (3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₄H₂₆ClN₅OS₂

: 1169705-55-8
(3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

Guidance literature:: With ammonia; In tetrahydrofuran; water; at 20 ℃;

Reference yield:

: 1169705-54-7
(3-{5-[3-(4-chloro-phenyl)-2-oxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

: 1169705-55-8
(3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

Guidance literature:: With tetraphosphorus decasulfide; In 5,5-dimethyl-1,3-cyclohexadiene; Reflux;
DOI:10.1016/j.bmcl.2009.09.037

Reference yield:

: C₂₀H₂₂ClN₃O₄

: 1169705-55-8
(3-{5-[3-(4-chloro-phenyl)-2-thioxo-imidazolidin-1-yl]-pentyloxy}-phenyl)-thiourea

Guidance literature:: Multi-step reaction with 4 steps

1: tetraphosphorus decasulfide / toluene / Heating / reflux

2: water; tin(ll) chloride / ethanol / 3 h / 70 °C

3: tetrahydrofuran / 3 h / 20 °C

4: ammonia / tetrahydrofuran; water / 20 °C

With tetraphosphorus decasulfide; ammonia; water; tin(ll) chloride; In tetrahydrofuran; ethanol; water; toluene;