(+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

Base Information

Chemical Name:(+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide
CAS No.:183146-40-9
Molecular Formula:C₁₉H₂₂N₄O₄
Molecular Weight:370.408
Hs Code.:

Synonyms:(+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

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Chemical Property of (+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

Chemical Property:

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Technology Process of (+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

There total 5 articles about (+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 5.0%

: 452-58-4
2,3-Diaminopyridine

: 4-(3-Isopropyl-2-oxo-oxazolidin-5-ylmethoxy)-benzoyl chloride

: 183146-40-9
(+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

: (+/-)-di-N,N'-(pyridine-2,3-diyl)-4,4'-bis[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

Guidance literature:: With pyridine; triethylamine; for 4h; Ambient temperature;

Reference yield:

: 99-76-3,156291-94-0
methyl 4-hydroxylbenzoate

: 183146-40-9
(+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaH / 1.) DMF, 0.5 h, 2.) DMF, 135 deg C, 5 h

2: 77 percent / 20percent aq. NaOH / methanol / 3 h / 45 °C

3: SOCl₂ / benzene / 4 h / Heating

4: 69 percent / Et₃N, pyridine / 4 h / Ambient temperature

With pyridine; sodium hydroxide; thionyl chloride; sodium hydride; triethylamine; In methanol; benzene;

Reference yield:

: 5-(chloromethyl)-3-isopropyloxazolidin-2-one

: 183146-40-9
(+/-)-N-(2-amino-3-pyridinyl)-4-[3-(1-methylethyl)-2-oxo-oxazolidin-5-ylmethoxy]benzamide

Guidance literature:: Multi-step reaction with 4 steps

1: 1.) NaH / 1.) DMF, 0.5 h, 2.) DMF, 135 deg C, 5 h

2: 77 percent / 20percent aq. NaOH / methanol / 3 h / 45 °C

3: SOCl₂ / benzene / 4 h / Heating

4: 69 percent / Et₃N, pyridine / 4 h / Ambient temperature

With pyridine; sodium hydroxide; thionyl chloride; sodium hydride; triethylamine; In methanol; benzene;