S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate

Base Information

Chemical Name:S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate
CAS No.:1373927-59-3
Molecular Formula:C₂₈H₂₂FNO₂S₂
Molecular Weight:487.619
Hs Code.:

Synonyms:S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate

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Technology Process of S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate

There total 2 articles about S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

: 449-81-0
(4Z)-2-phenyl-4-[(4-fluorophenyl)methylidene]-1,3-oxazol-5(4H)-one

: 108-98-5
thiophenol

: 1373927-59-3
S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate

Guidance literature:: thiophenol; With 1-{3,5-bis(trifluoromethyl)phenyl}-3-{(1R,2R)-2-(dimethylamino)cyclohexyl}thiourea; In chlorobenzene; at -20 ℃; for 0.5h;

(4Z)-2-phenyl-4-[(4-fluorophenyl)methylidene]-1,3-oxazol-5(4H)-one; In chlorobenzene; at -20 ℃; for 18h; optical yield given as %ee; enantioselective reaction;
DOI:10.1039/c2cc30799e

Reference yield:

: 449-81-0
(4Z)-2-phenyl-4-[(4-fluorophenyl)methylidene]-1,3-oxazol-5(4H)-one

: 108-98-5
thiophenol

: 1373927-59-3
S-phenyl (2S,3R)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate

: S-phenyl (2R,3S)-2-benzamido-3-(4-fluorophenyl)-3-(phenylthio)propanethioate

Guidance literature:: thiophenol; With 1-{3,5-bis(trifluoromethyl)phenyl}-3-{(1R,2R)-2-(dimethylamino)cyclohexyl}thiourea; In chlorobenzene; at -20 ℃; for 0.5h;

(4Z)-2-phenyl-4-[(4-fluorophenyl)methylidene]-1,3-oxazol-5(4H)-one; In chlorobenzene; at -20 ℃; for 18h; optical yield given as %ee; enantioselective reaction;
DOI:10.1039/c2cc30799e