Technology Process of C31H46N4OSi
There total 8 articles about C31H46N4OSi which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium phosphate; 2-(dicyclohexylphosphino)-2'-methylbiphenyl;
tris(dibenzylideneacetone)dipalladium (0);
In
1,2-dimethoxyethane;
at 100 ℃;
for 0.333333h;
under 3102.97 Torr;
microwave irradiation;
DOI:10.1016/j.bmcl.2007.06.077
- Guidance literature:
-
Multi-step reaction with 4 steps
1: aq. HCl / 1.5 h / 70 °C
2: NaBH4 / methanol / 1 h / 0 °C
3: imidazole; DMAP / dimethylformamide / 20 °C
4: 2-(dicyclohexylphosphino)-2'-methylbiphenyl; K3PO4 / Pd2(dba)3 / 1,2-dimethoxy-ethane / 0.33 h / 100 °C / 3102.97 Torr / microwave irradiation
With
1H-imidazole; hydrogenchloride; dmap; sodium tetrahydroborate; potassium phosphate; 2-(dicyclohexylphosphino)-2'-methylbiphenyl;
tris(dibenzylideneacetone)dipalladium (0);
In
methanol; 1,2-dimethoxyethane; N,N-dimethyl-formamide;
4: Buchwald amination;
DOI:10.1016/j.bmcl.2007.06.077
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: BuLi / tetrahydrofuran / 0.17 h / 0 °C
1.2: tetrahydrofuran / 20 °C
2.1: aq. HCl / 1.5 h / 70 °C
3.1: NaBH4 / methanol / 1 h / 0 °C
4.1: imidazole; DMAP / dimethylformamide / 20 °C
5.1: 2-(dicyclohexylphosphino)-2'-methylbiphenyl; K3PO4 / Pd2(dba)3 / 1,2-dimethoxy-ethane / 0.33 h / 100 °C / 3102.97 Torr / microwave irradiation
With
1H-imidazole; hydrogenchloride; dmap; sodium tetrahydroborate; potassium phosphate; n-butyllithium; 2-(dicyclohexylphosphino)-2'-methylbiphenyl;
tris(dibenzylideneacetone)dipalladium (0);
In
tetrahydrofuran; methanol; 1,2-dimethoxyethane; N,N-dimethyl-formamide;
5.1: Buchwald amination;
DOI:10.1016/j.bmcl.2007.06.077