α-bromo phenylacetic acid allyl ester

Base Information

• Chemical Name: α-bromo phenylacetic acid allyl ester
• CAS No.: 99853-19-7
• Molecular Formula: C₁₁H₁₁BrO₂
• Molecular Weight: 255.111
• Mol file: 99853-19-7.mol

Synonyms:α-bromo phenylacetic acid allyl ester

Chemical Property of α-bromo phenylacetic acid allyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-bromo phenylacetic acid allyl ester

There total 5 articles about α-bromo phenylacetic acid allyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

allyl α-phenyl-α-diazoacetate (145193-16-4) → α-bromo phenylacetic acid allyl ester (99853-19-7)

Guidance literature:

With cobalt(II) bromide hexahydrate; In 1,4-dioxane; at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1002/adsc.202000009

Reference yield: 29.0%

allyl dibromoacetate (90448-98-9) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → α-bromo phenylacetic acid allyl ester (99853-19-7) + 3-Bromo-4-bromomethyl-dihydro-furan-2-one + 4-Bromomethyl-3-phenyl-dihydro-furan-2-one

Guidance literature:

With iron pentacarbonyl; N,N-dimethyl-formamide; at 140 - 150 ℃; for 3h;

DOI:10.1007/BF02495259

Reference yield: 12.0%

allyl dibromoacetate (90448-98-9) → α-bromo phenylacetic acid allyl ester (99853-19-7) + 3-Bromo-4-bromomethyl-dihydro-furan-2-one + 4-Bromomethyl-3-phenyl-dihydro-furan-2-one

Guidance literature:

With iron pentacarbonyl; N,N-dimethyl-formamide; In benzene; at 140 - 150 ℃; for 3h;

DOI:10.1007/BF02495259

upstream raw materials:

allyl dibromoacetate

benzene

phenylacetic acid

α-bromophenylacetyl bromide

Downstream raw materials:

allyl 4-oxo-2,4-diphenylbutanoate

2-(3-cyano-4-furan-2-yl-6-thiophen-2-yl-pyridin-2-yloxy)-2-phenyl-N-(2H-tetrazol-5-yl)-acetamide

N-methyl-N-(1-phenylbut-3-enyl)aniline

Refernces

• 1、 Hu, Bei,Chen, Haixia,Liu, Yan,Dong, Wuheng,Ren, Kai,Xie, Xiaomin,Xu, Hao,Zhang, Zhaoguo. "Visible light-induced intermolecular radical addition: Facile access to γ-ketoesters from alkyl-bromocarboxylates and enamines". . p. 13547 - 13550. Retrieved 2015/01/09.