((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide

Base Information

• Chemical Name: ((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide
• CAS No.: 38399-21-2
• Molecular Formula: Br*C₂₉H₂₃BrP
• Molecular Weight: 562.283
• Mol file: 38399-21-2.mol

Synonyms:((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide

Chemical Property of ((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide

There total 2 articles about ((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-bromo-3-(bromomethyl)naphthalene (38399-20-1) + triphenylphosphine (603-35-0) → ((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide (38399-21-2)

Guidance literature:

In N,N-dimethyl-formamide; at 25 ℃; for 12h;

DOI:10.1021/jacs.0c05611

Reference yield:

2-bromo-3-carboxynaphthalene (20717-80-0) → ((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide (38399-21-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) LiAlH₄, (ii) PBr₃, Py

Reference yield: 69.0%

((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide (38399-21-2) + 3-bromo-2-naphthalenecarboxaldehyde (89005-11-8) → (Z)-1,2-bis(3-bromonaphthalen-2-yl)ethene

Guidance literature:

((3-bromonaphthalen-2-yl)methyl)triphenylphosphonium bromide; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; Inert atmosphere;

3-bromo-2-naphthalenecarboxaldehyde; In tetrahydrofuran; at 0 - 20 ℃; optical yield given as %de; stereoselective reaction; Inert atmosphere;

DOI:10.1002/anie.200902803

upstream raw materials:

2-bromo-3-(bromomethyl)naphthalene

triphenylphosphine

2-bromo-3-carboxynaphthalene

Downstream raw materials:

2-Bromo-3-[1,2-dibromo-2-(2-bromo-phenyl)-ethyl]-naphthalene

2-Bromo-3-(2-bromo-phenylethynyl)-naphthalene

C₁₈H₁₀Br₄

(Z)-2-bromo-3-(2-bromostyryl)naphthalene

Refernces

• 1、 -. "COMPOUND AND POLYMER COMPOUND CONTAINING THE COMPOUND". Paragraph 0184-0186. . Retrieved 2021/01/26.