benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

Base Information

Chemical Name:benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate
CAS No.:640291-23-2
Molecular Formula:C₂₈H₄₀Cl₆N₂O₁₁Si
Molecular Weight:821.436
Hs Code.:

Synonyms:benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

Suppliers and Price of benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

There total 5 articles about benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1078691-95-8
(+)-D-glucosamine hydrochloride

: 640291-23-2
benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium hydrogencarbonate / water / 20 °C

2.1: pyridine / water / 0 - 20 °C

3.1: boron trifluoride diethyl etherate / dichloromethane / 48 h / 0 - 20 °C / Inert atmosphere

3.2: 20 °C / Inert atmosphere

4.1: ammonium hydroxide / methanol / 48 h / 20 °C

5.1: sodium hydrogencarbonate; tetrabutylammomium bromide / water; dichloromethane

6.1: pyridine / 3 h

With pyridine; ammonium hydroxide; boron trifluoride diethyl etherate; tetrabutylammomium bromide; sodium hydrogencarbonate; In methanol; dichloromethane; water;
DOI:10.1021/acs.jmedchem.0c00851

Reference yield:

: 640291-22-1
N-trichloroethoxycarbonyl-O-[3,4,6-tri-O-acetyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serine

: 640291-23-2
benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

Guidance literature:: Multi-step reaction with 3 steps

1: ammonium hydroxide / methanol / 48 h / 20 °C

2: sodium hydrogencarbonate; tetrabutylammomium bromide / water; dichloromethane

3: pyridine / 3 h

With pyridine; ammonium hydroxide; tetrabutylammomium bromide; sodium hydrogencarbonate; In methanol; dichloromethane; water;
DOI:10.1021/acs.jmedchem.0c00851

Reference yield:

: 122210-01-9,122210-05-3,145416-95-1,146864-65-5,114360-77-9
1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-D-glucopyranose

: 640291-23-2
benzyl N-trichloroethoxycarbonyl-O-[6-O-tert-butyldimethylsilyl-2-N-trichloroethoxycarbonyl-β-D-glucopyranosyl]-L-serinate

Guidance literature:: Multi-step reaction with 4 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 48 h / 0 - 20 °C / Inert atmosphere

1.2: 20 °C / Inert atmosphere

2.1: ammonium hydroxide / methanol / 48 h / 20 °C

3.1: sodium hydrogencarbonate; tetrabutylammomium bromide / water; dichloromethane

4.1: pyridine / 3 h

With pyridine; ammonium hydroxide; boron trifluoride diethyl etherate; tetrabutylammomium bromide; sodium hydrogencarbonate; In methanol; dichloromethane; water;
DOI:10.1021/acs.jmedchem.0c00851