E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile

Base Information

Chemical Name:E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile
CAS No.:934753-81-8
Molecular Formula:C₃₄H₃₇N₃O₃
Molecular Weight:535.686
Hs Code.:

Synonyms:E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile

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Chemical Property of E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile

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Technology Process of E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile

There total 1 articles about E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1218938-87-4
C₃₃H₃₉N₃O₂

: 503-38-8
trichloromethyl chloroformate

: 934753-81-8
E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile

Guidance literature:: In 1,4-dioxane; for 1h; Reflux;

Reference yield: 24.0%

: 934753-81-8
E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile

: 934754-83-3
E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro-[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enoic acid

Guidance literature:: E-8-[2-(4-tert-Butylbenzyloxy)phenyl]-6-[4-(5-oxo-4,5-dihydro[1,3,4]oxadiazol-2-yl)benzyl]oct-7-enenitrile; With propan-1-ol; potassium hydroxide; at 110 ℃; for 15h;

With hydrogenchloride; water; In propan-1-ol; pH=4;