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Technology Process of N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide

N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide

Base Information
  • Chemical Name:N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide
  • CAS No.:527719-35-3
  • Molecular Formula:C28H40F2N4O4
  • Molecular Weight:534.647
  • Hs Code.:
N<sub>3</sub>-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N<sub>1</sub>,N<sub>1</sub>-dipropyl-beta-alaninamide

Synonyms:N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide

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Chemical Property of N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide
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Technology Process of N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide

There total 2 articles about N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

{4-(3,5-difluoro-phenyl)-3-[3-(2-dipropylcarbamoyl-ethyl)-ureido]-2-hydroxy-butyl}-(3-methoxybenzyl)-carbamic acid benzyl ester
700866-69-9

{4-(3,5-difluoro-phenyl)-3-[3-(2-dipropylcarbamoyl-ethyl)-ureido]-2-hydroxy-butyl}-(3-methoxybenzyl)-carbamic acid benzyl ester

N<sub>3</sub>-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N<sub>1</sub>,N<sub>1</sub>-dipropyl-beta-alaninamide
527719-35-3

N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide

Guidance literature:
With ammonium acetate; hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 1.5h;

Reference yield:

N<sub>3</sub>-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N<sub>1</sub>,N<sub>1</sub>-dipropyl-beta-alaninamide
527719-35-3

N3-[({(1S,2R)-1-(3,5-difluorobenzyl)-2-hydroxy-3-[(3-methoxybenzyl)amino]propyl}amino)carbonyl]-N1,N1-dipropyl-beta-alaninamide

Guidance literature:
upstream raw materials:

{4-(3,5-difluoro-phenyl)-3-[3-(2-dipropylcarbamoyl-ethyl)-ureido]-2-hydroxy-butyl}-(3-methoxybenzyl)-carbamic acid benzyl ester

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