3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid

Base Information

• Chemical Name: 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid
• CAS No.: 179083-72-8
• Molecular Formula: C₁₅H₂₁NO₅
• Molecular Weight: 295.335
• Mol file: 179083-72-8.mol

Synonyms:3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid

Chemical Property of 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid

There total 1 articles about 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methyl 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoate (179083-71-7) → 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid (179083-72-8)

Guidance literature:

methyl 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoate; With water; sodium hydroxide; In tetrahydrofuran; at 20 ℃;

With sodium hydrogen sulfate; In water;

DOI:10.1016/j.bmc.2010.01.049

Reference yield: 89.0%

N1-isopropyl-N1-(4-methoxyphenyl)glycinamide (173944-93-9) + 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid (179083-72-8) → N-(2,2-diethoxyethyl)-N-phenyl-N'-(2-(isopropyl(4-methoxyphenyl)amino)-2-oxoethyl)malonamide (179083-73-9)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 ℃;

DOI:10.1016/j.bmc.2010.01.049

Reference yield:

3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoic acid (179083-72-8) + N1-isopropyl-N1-(4-fluorophenyl)glycinamide (1224605-40-6) → C26H34FN3O5

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In N,N-dimethyl-formamide; at 0 ℃;

DOI:10.1016/j.bmc.2010.01.049

upstream raw materials:

methyl 3-[(N-2,2-diethoxyethyl)-N-phenyl]amino-3-oxopropanoate

Downstream raw materials:

N-(2,2-diethoxyethyl)-N-phenyl-N'-(2-(isopropyl(4-methoxyphenyl)amino)-2-oxoethyl)malonamide