Technology Process of C41H52N6O10
There total 31 articles about C41H52N6O10 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydrogenchloride;
In
ethyl acetate;
at 25 ℃;
for 1h;
Yield given;
DOI:10.1021/ja00004a062
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 97 percent / PyBrOP; diisopropylethylamine / dimethylformamide / 0 - 20 °C
2.1: trifluoroacetic acid / 0.33 h / 20 °C
2.2: 63 percent / diisopropylethylamine; 1-hydroxybenzotriazole; 1-(3-dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride / CH2Cl2 / 24 h / 20 °C
3.1: 82 percent / LiOH*H2O / tetrahydrofuran; methanol; H2O / 1 h / 20 °C
4.1: HCl / ethyl acetate / 1 h
With
hydrogenchloride; lithium hydroxide; N-ethyl-N,N-diisopropylamine; bromo-tris(1-pyrrolidinyl)phosphonium hexafluorophosphate; trifluoroacetic acid;
In
tetrahydrofuran; methanol; water; ethyl acetate; N,N-dimethyl-formamide;
1.1: coupling / 2.1: Hydrolysis / 2.2: coupling / 3.1: Hydrolysis / 4.1: Hydrolysis;
DOI:10.1021/jo990432w
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 69 percent / EDCI, HOBt*H2O / dimethylformamide / 16 h / 25 °C
2: NaH, CuBr-SMe2, collidine / 8 h / 130 °C
3: 98 percent / H2 / 10percent Pd/C / methanol / 6 h / 25 °C / 760 Torr
4: 53 percent / EDCI, HOBt*H2O / dimethylformamide / 16 h / 25 °C
5: LiOH*H2O / tetrahydrofuran; methanol; H2O / 2 h / 25 °C
6: HCl / ethyl acetate / 1 h / 25 °C
With
2,3,5-trimethyl-pyridine; hydrogenchloride; lithium hydroxide; hydrogen; sodium hydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; water; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1021/ja00004a062
