1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

Base Information

Chemical Name:1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol
CAS No.:106295-31-2
Molecular Formula:C₂₉H₃₁NO₅
Molecular Weight:473.569
Hs Code.:

Synonyms:1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

Suppliers and Price of 1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

There total 15 articles about 1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 106265-18-3
2L-(2,4,5/3) 2,3-di-O-benzyloxy-4-N-benzyl-4-N-benzyloxycarbonyl-amino-5-hydroxy-cyclohexanone

: 106295-31-2
1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

Guidance literature:: Multi-step reaction with 2 steps

1: 60 percent / 1,2-dimethoxy-ethane / 0.75 h / -5 - 10 °C

2: 1.) mercury(II) acetate, 2.) aq. KI, NaBH₄ / 1.) H₂O, CH₃CN

With sodium tetrahydroborate; mercury(II) diacetate; potassium iodide; In 1,2-dimethoxyethane;
DOI:10.1039/c39860001399

Reference yield:

: Benzyl-((2S,3R,4R,5S)-4,5-bis-benzyloxy-2-methoxy-6-methylene-tetrahydro-pyran-3-yl)-carbamic acid phenyl ester

: 106295-31-2
1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

Guidance literature:: Multi-step reaction with 3 steps

1: HgSO₄, 5 mM H₂SO₄ / dioxane; H₂O / 2 h / 80 °C

3: 1.) mercury(II) acetate, 2.) NaBH₄ / 1.) acetonitrile, H₂O

With sodium tetrahydroborate; sulfuric acid; mercury(II) diacetate; mercury(II) sulfate; In 1,4-dioxane; water;
DOI:10.1021/jo00277a002

Reference yield:

: 102997-59-1
2-amino-N-benzyl-N-benzyloxycarbonyl-3,4-di-O-benzyl-2-deoxy-1-O-methyl-α-D-gluco-hex-5-enopyranoside

: 106295-31-2
1D-(1,2,4,5/3)-3,4-di-O-benzyl-2-benzylamino-1,2-N,O-carbonyl-5-C-hydroxy-methyl-1,3,4-cyclohexanetriol

Guidance literature:: Multi-step reaction with 3 steps

1: 18.2 g / HgSO₄, aq. H₂SO₄ / dioxane / 3 h / 80 °C

2: n-BuLi / 1) 1,2-dimethoxyethane, -70 - 0 deg C, 2) 0 deg C, 45 min

3: 1) diborane, 2) aq. NaOH, H₂O₂ / 1) THF, room temperature, overnight, 2) overnight

With sodium hydroxide; n-butyllithium; sulfuric acid; dihydrogen peroxide; mercury(II) sulfate; diborane; In 1,4-dioxane;
DOI:10.1016/S0040-4020(01)97594-5