(3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Base Information

• Chemical Name: (3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole
• CAS No.: 162757-77-9
• Molecular Formula: C₂₈H₃₀N₂O₄
• Molecular Weight: 458.557
• Mol file: 162757-77-9.mol

Synonyms:(3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Chemical Property of (3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

There total 1 articles about (3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 16.0%

methyl chloroformate (79-22-1) + (3S/R,3α/β)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole → (3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole (162757-77-9) + (3R,3β)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Guidance literature:

With triethylamine; In dichloromethane; for 0.5h;

DOI:10.1021/jo00113a034

Reference yield: 93.0%

(3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole (162757-77-9) → (3S,3α)-1-<(1S,2S)-<<1-(Hydroxymethyl)cyclohex-4-en-2-yl>methyl>>-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Guidance literature:

With sodium hydroxide; In ethylene glycol; at 130 ℃; for 36h;

DOI:10.1021/jo00113a034

Reference yield: 83.0%

(3S,3α)-1-<(1S,2S)-<<1-<(Benzoyloxy)methyl>cyclohex-4-en-2-yl>methyl>>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole (162757-77-9) → (3S,3α)-1-<(1S*,2R*,4S,5R)-<1,2-Dihydroxy-4-<(benzoyloxy)methyl>cyclohex-5-yl>methyl>-2-(methoxycarbonyl)-2,3,4,9-tetrahydro-1H-pyrido<3,4-b>indole

Guidance literature:

With osmium(VIII) oxide; 4-methylmorpholine N-oxide; In tetrahydrofuran; water; tert-butyl alcohol; for 12h; Ambient temperature;

DOI:10.1021/jo00113a034

upstream raw materials:

methyl chloroformate