(2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol

Base Information

• Chemical Name: (2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol
• CAS No.: 211994-43-3
• Molecular Formula: C₂₀H₂₄N₆O₆
• Molecular Weight: 444.447
• Mol file: 211994-43-3.mol

Synonyms:(2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol

Chemical Property of (2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of (2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol

There total 1 articles about (2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

(4R,5R)-4,5-Bis-[(S)-1-azido-2-(4-methoxy-phenoxy)-ethyl]-2,2-dimethyl-[1,3]dioxolane (211994-34-2) → (2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol (211994-43-3)

Guidance literature:

With acetyl chloride; In methanol; at 20 ℃; for 4h;

DOI:10.1016/S0968-0896(02)00643-0

Reference yield: 81.0%

di-tert-butyl dicarbonate (24424-99-5) + (2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol (211994-43-3) → [(1S,2R,3R,4S)-4-tert-Butoxycarbonylamino-2,3-dihydroxy-5-(4-methoxy-phenoxy)-1-(4-methoxy-phenoxymethyl)-pentyl]-carbamic acid tert-butyl ester

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate;

DOI:10.1021/jo971562c

Reference yield:

(2S,3R,4R,5S)-2,5-Diazido-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol (211994-43-3) → (2S,3R,4R,5S)-2,5-Diamino-1,6-bis-(4-methoxy-phenoxy)-hexane-3,4-diol

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 1h; atmospheric pressure;

DOI:10.1016/S0968-0896(02)00643-0

upstream raw materials:

(4R,5R)-4,5-Bis-[(S)-1-azido-2-(4-methoxy-phenoxy)-ethyl]-2,2-dimethyl-[1,3]dioxolane