(cis:trans)-(-)-lobeline

Base Information

• Chemical Name: (cis:trans)-(-)-lobeline
• CAS No.: 1070913-26-6
• Molecular Formula: C₂₂H₂₇NO₂
• Molecular Weight: 337.462
• Mol file: 1070913-26-6.mol

Synonyms:(cis:trans)-(-)-lobeline

Chemical Property of (cis:trans)-(-)-lobeline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (cis:trans)-(-)-lobeline

There total 1 articles about (cis:trans)-(-)-lobeline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(-)-lobeline semisulfate salt → (cis:trans)-(-)-lobeline (1070913-26-6)

Guidance literature:

With potassium carbonate; In methanol; at 20 ℃; for 48h;

DOI:10.1021/jm0501228

Reference yield:

(cis:trans)-(-)-lobeline (1070913-26-6) → Lobeline hydrochloride (134-63-4)

Guidance literature:

With hydrogenchloride; In water; isopropyl alcohol; at 60 ℃; for 8h; Inert atmosphere;

DOI:10.1021/ja804738b

Reference yield:

(cis:trans)-(-)-lobeline (1070913-26-6) → (S)-2-[(S)-6-(2-Hydroxy-2-phenyl-ethyl)-1-methyl-piperidin-2-yl]-1-phenyl-ethanol

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 20 ℃; for 1h;

DOI:10.1021/jm0501228

Downstream raw materials:

(2S,6R)-1-Methyl-2,6-bis-((E)-styryl)-piperidine

(2S,6S)-trans-lobelane

N-methyl-2,6-di-(cis-phenylethyl)piperidine

(2S,6S)-1-Methyl-2,6-bis-((E)-styryl)-piperidine

Refernces