5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

Base Information

Chemical Name:5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole
CAS No.:114798-92-4
Molecular Formula:C₂₄H₂₅ClN₂O₄
Molecular Weight:440.927
Hs Code.:

Synonyms:5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

Suppliers and Price of 5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

There total 7 articles about 5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 114798-90-2
2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloro-5-(hydroxymethyl)imidazole

: 108-24-7
acetic anhydride

: 114798-92-4
5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

Guidance literature:: With dmap; triethylamine; In tetrahydrofuran; at 25 ℃; for 4.5h;
DOI:10.1021/jm00167a008

Reference yield:

: 624-31-7
4-tolyl iodide

: 114798-92-4
5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

Guidance literature:: Multi-step reaction with 5 steps

1: 35 percent / Cu / 1 h / 210 °C

2: N-bromosuccinimide, azobisisobutyronitrile / CCl₄ / 3 h / Heating

3: 1.) sodium methoxide / 1.) DMF, 25 deg C, 0.25 h, 2.) 40 deg C, 4 h

4: 83 percent / NaOH / ethanol; H₂O / 5 h / Heating

5: 59 percent / 4-(dimethylamino)pyridine, triethylamine / tetrahydrofuran / 4.5 h / 25 °C

With dmap; sodium hydroxide; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); sodium methylate; copper; triethylamine; In tetrahydrofuran; tetrachloromethane; ethanol; water;
DOI:10.1021/jm00167a008

Reference yield:

: 618-91-7
methyl 3-iodo-benzoate

: 114798-92-4
5-(acetoxymethyl)-2-butyl-1-<(3'-carboxybiphenyl-4-yl)methyl>-4-chloroimidazole

Guidance literature:: Multi-step reaction with 5 steps

1: 35 percent / Cu / 1 h / 210 °C

2: N-bromosuccinimide, azobisisobutyronitrile / CCl₄ / 3 h / Heating

3: 1.) sodium methoxide / 1.) DMF, 25 deg C, 0.25 h, 2.) 40 deg C, 4 h

4: 83 percent / NaOH / ethanol; H₂O / 5 h / Heating

5: 59 percent / 4-(dimethylamino)pyridine, triethylamine / tetrahydrofuran / 4.5 h / 25 °C

With dmap; sodium hydroxide; N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); sodium methylate; copper; triethylamine; In tetrahydrofuran; tetrachloromethane; ethanol; water;
DOI:10.1021/jm00167a008