Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal

Base Information

• Chemical Name: Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal
• CAS No.: 245365-58-6
• Molecular Formula: C₇₇H₇₉NO₁₇
• Molecular Weight: 1290.47
• Mol file: 245365-58-6.mol

Synonyms:Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal

Chemical Property of Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal

There total 1 articles about Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

Methyl 2,6-di-O-benzyl-3-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-α-D-mannopyranoside-trichloroacetimidate 3'',4''-di-O-benzyl-2''-deoxy-2''-phthalimido-β-D-glucopyranoside-4,6''-methylidene acetal → Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal (245365-58-6)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; In dichloromethane; at -20 ℃; for 0.166667h;

DOI:10.1002/(SICI)1521-3765(19990802)5:8<2281::AID-CHEM2281>3.0.CO;2-D

Reference yield:

Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal (245365-58-6) → C69H77NO15

Guidance literature:

With hydrazine hydrate; In ethanol; for 18h; Heating;

DOI:10.1002/(SICI)1521-3765(19990802)5:8<2281::AID-CHEM2281>3.0.CO;2-D

Reference yield:

Methyl (3,4-di-O-benzyl-2-deoxy-2-phthalimido-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal (245365-58-6) → Methyl (3,4-di-O-benzyl-2-acetimido-2-deoxy-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal (245365-59-7)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine monohydrate / ethanol / 18 h / Heating

2: pyridine / 4 h / 20 °C

With pyridine; hydrazine hydrate; In ethanol; 1: Hydrolysis / 2: Acetylation;

DOI:10.1002/(SICI)1521-3765(19990802)5:8<2281::AID-CHEM2281>3.0.CO;2-D

Downstream raw materials:

Methyl (3,4-di-O-benzyl-2-acetimido-2-deoxy-β-D-glucopyranosyl)(1->2)-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->3)-2,6-di-O-benzyl-α-D-mannopyranoside-4,6''-methylidene acetal