1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea

Base Information

• Chemical Name: 1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea
• CAS No.: 1101171-78-1
• Molecular Formula: C₂₉H₃₂N₄O₃S₂
• Molecular Weight: 548.73

Synonyms:1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea

Chemical Property of 1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea

Chemical Property:

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Technology Process of 1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea

There total 1 articles about 1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.4%

N-(4-(2-aminothiazol-4-yl)phenyl)methanesulfonamide (476338-85-9) + N-isopropyl-3,3-diphenylpropan-1-amine (159149-65-2) + 1,1'-carbonyldiimidazole (530-62-1) → 1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea (1101171-78-1)

Guidance literature:

N-(4-(2-aminothiazol-4-yl)phenyl)methanesulfonamide; 1,1'-carbonyldiimidazole; With dmap; In N,N-dimethyl-formamide; at 20 ℃; for 40h;

N-isopropyl-3,3-diphenylpropan-1-amine; In N,N-dimethyl-formamide; at 20 - 40 ℃; for 23h;

Reference yield:

1-(3,3-diphenylpropyl)-1-isopropyl-3-(4-(4-(methylsulfonamido)phenyl)thiazol-2-yl)urea (1101171-78-1) → N-(4-(5-chloro-2-(((3,3-diphenylpropyl)(1-methylethyl)carbamoyl)amino)-1,3-thiazol-4-yl)phenyl)methanesulfonamide (1101172-11-5)

Guidance literature:

With N-chloro-succinimide; In N,N-dimethyl-formamide; at 20 ℃; for 48h;

upstream raw materials:

N-(4-(2-aminothiazol-4-yl)phenyl)methanesulfonamide

N-isopropyl-3,3-diphenylpropan-1-amine

1,1'-carbonyldiimidazole

Downstream raw materials:

N-(4-(5-chloro-2-(((3,3-diphenylpropyl)(1-methylethyl)carbamoyl)amino)-1,3-thiazol-4-yl)phenyl)methanesulfonamide

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