Ronidazole

Base Information

Chemical Name:Ronidazole
CAS No.:7681-76-7
Molecular Formula:C6H8N4O4
Molecular Weight:200.154
Hs Code.:29332900
European Community (EC) Number:231-675-1
NSC Number:757865
UNII:E01R4M1063
DSSTox Substance ID:DTXSID6045400
Nikkaji Number:J2.265I
Wikipedia:Ronidazole
Wikidata:Q7365706
NCI Thesaurus Code:C152248
RXCUI:1535498
ChEMBL ID:CHEMBL290299
Mol file:7681-76-7.mol

Synonyms:Ridzol;Ronida;Ronidazol;Ronidazole

Suppliers and Price of Ronidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Ronidazole
500ul
$ 523.00

Usbiological
Ronidazole
500ul
$ 654.00

TRC
Ronidazole
1g
$ 145.00

Sigma-Aldrich
Ronidazole analytical standard
5g
$ 22.60

Medical Isotopes, Inc.
Ronidazole
10 g
$ 1460.00

Crysdot
Ronidazole 98+%
25g
$ 120.00

ChemScene
Ronidazole 99.79%
500mg
$ 50.00

ChemScene
Ronidazole 99.79%
1g
$ 72.00

ChemScene
Ronidazole 99.79%
5g
$ 108.00

American Custom Chemicals Corporation
RONIDAZOLE 95.00%
10G
$ 618.00

Total 124 raw suppliers

Chemical Property of Ronidazole

Chemical Property:

Vapor Pressure:3.21E-10mmHg at 25°C
Melting Point:167-169°
Refractive Index:1.651
Boiling Point:502.3 °C at 760 mmHg
PKA:1.2(at 25℃)
Flash Point:257.6 °C
PSA：115.96000
Density:1.65 g/cm³
LogP:1.14710
Storage Temp.:−20°C
Solubility.:DMSO (Slightly), Methanol (Slightly, Heated)
XLogP3:-0.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:200.05455475
Heavy Atom Count:14
Complexity:241

Purity/Quality:

99% ^*data from raw suppliers

Ronidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1C(=CN=C1COC(=O)N)[N+](=O)[O-]
Uses antibacterial

Technology Process of Ronidazole

There total 3 articles about Ronidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 263159-60-0
(1-methyl-5-nitro-1H-imidazol-2-yl)methyl 4-nitrophenyl carbonate

: 7681-76-7
ronidazole

Guidance literature:: With ammonium hydroxide; In dichloromethane; at 0 - 10 ℃; for 3h; Inert atmosphere;
DOI:10.1021/acs.jmedchem.9b02097

Reference yield:

: 936-05-0
1-methyl-2-hydroxymethyl-5-nitroimidazole

: 7681-76-7
ronidazole

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 20 °C / Inert atmosphere

2: ammonium hydroxide / dichloromethane / 3 h / 0 - 10 °C / Inert atmosphere

With ammonium hydroxide; triethylamine; In dichloromethane;
DOI:10.1021/acs.jmedchem.9b02097