Technology Process of 4-((2,3-dimethyl-4-oxo-4,5,6,7-tetrahydroindol-1-yl)methyl)-N-hydroxybenzamide
There total 3 articles about 4-((2,3-dimethyl-4-oxo-4,5,6,7-tetrahydroindol-1-yl)methyl)-N-hydroxybenzamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
methyl 4-((2,3-dimethyl-4-oxo-4,5,6,7-tetrahydroindol-1-yl)methyl)benzoate;
With
hydroxylamine hydrochloride; potassium hydroxide;
In
methanol;
for 0.166667h;
With
hydroxylamine;
In
methanol; water;
at 20 ℃;
for 4h;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: acetic acid; zinc / water / 12 h / 0 °C / Heating
2.1: sodium hydride / N,N-dimethyl-formamide; paraffin oil / 0.17 h
2.2: 5 h / 50 °C
3.1: hydroxylamine hydrochloride; potassium hydroxide; hydroxylamine / methanol; water / 4 h / 20 °C
With
hydroxylamine hydrochloride; hydroxylamine; sodium hydride; acetic acid; potassium hydroxide; zinc;
In
methanol; water; N,N-dimethyl-formamide; paraffin oil;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: sodium hydride / N,N-dimethyl-formamide; paraffin oil / 0.17 h
1.2: 5 h / 50 °C
2.1: hydroxylamine hydrochloride; potassium hydroxide; hydroxylamine / methanol; water / 4 h / 20 °C
With
hydroxylamine hydrochloride; hydroxylamine; sodium hydride; potassium hydroxide;
In
methanol; water; N,N-dimethyl-formamide; paraffin oil;
