dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

Base Information

Chemical Name:dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate
CAS No.:1279110-12-1
Molecular Formula:C₂₅H₃₀N₄O₄Si
Molecular Weight:478.623
Hs Code.:

Synonyms:dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

Suppliers and Price of dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

There total 1 articles about dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 329191-55-1
(2S,4S)-N^α-Cbz-4-azidoproline benzyl ester

: 1066-54-2
trimethylsilylacetylene

: 1279110-12-1
dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

Guidance literature:: With copper(II) sulfate; sodium L-ascorbate; In water; tert-butyl alcohol; at 20 ℃;
DOI:10.1016/j.tet.2011.01.031

Reference yield: 94.0%

: 1279110-12-1
dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

: 1279110-13-2
dibenzyl (2S,4S)-4-(1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

Guidance literature:: With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 6h;
DOI:10.1016/j.tet.2011.01.031

Reference yield:

: 1279110-12-1
dibenzyl (2S,4S)-4-(4-(trimethylsilyl)-1H-1,2,3-triazol-1-yl)pyrrolidine-1,2-dicarboxylate

: BF₄^(1-)*C₂₃H₂₅N₄O₄⁽¹⁺⁾

Guidance literature:: Multi-step reaction with 3 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 6 h / 20 °C

2: acetonitrile / Inert atmosphere; Reflux

3: silver tetrafluoroborate / methanol

With silver tetrafluoroborate; tetrabutyl ammonium fluoride; In tetrahydrofuran; methanol; acetonitrile;
DOI:10.1016/j.tet.2011.01.031