4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide

Base Information

Chemical Name:4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide
CAS No.:1357279-01-6
Molecular Formula:C₂₅H₃₁N₅O₅S
Molecular Weight:513.618
Hs Code.:

Synonyms:4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide

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Chemical Property of 4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide

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Technology Process of 4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide

There total 1 articles about 4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1357279-00-5
N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-4-chloro-3-nitrobenzenesulfonamide

: 100-46-9
benzylamine

: 1357279-01-6
4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide

Guidance literature:: at 80 ℃; for 0.166667h;

Reference yield:

: 1357279-01-6
4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide

: 1357279-02-7
3,4-diamino-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)benzenesulfonamide

Guidance literature:: With ammonium formate; palladium 10% on activated carbon; In methanol; at 50 ℃; for 2h;

Reference yield:

: 1357279-01-6
4-(benzylamino)-N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-3-nitrobenzenesulfonamide

: 1357271-78-3
N-((1r,1r)-4-(5-tert-butyl-1,3,4-oxadiazol-2-yl)cyclohexyl)-2-(4-(4-methylpiperazin-1-yl)phenylamino)-1H-benzo[d]imidazole-5-sulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium formate / palladium 10% on activated carbon / methanol / 2 h / 50 °C

2: polymer-supported carbodiimide / tetrahydrofuran / 16 h / 70 °C

With ammonium formate; palladium 10% on activated carbon; In tetrahydrofuran; methanol;